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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

ERK1 (aa190-208) Phospho aa202

pERK1 Thr202 Peptide (aa 190-208) Aptamer

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
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ATW0092-100pERK1 Thr202 Peptide (aa 190-208) Aptamer10 AEU (100ug) POA Quantity Add to Order
ATW0092-25pERK1 Thr202 Peptide (aa 190-208) Aptamer2.5 AEU (25ug) POA Quantity Add to Order

Description

ATW0092 Aptamer to Phosphorylated ERK1 Thr202 (aa 190-208) Peptide

ERK1 (Mitogen-activated protein kinase 3, also known as ERK1) is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and phosphorylated aa202 ERK1 (aa 190-208) peptide CIADPEHDHTGFL(t)EYVATR as a target and 1X PBS, 1mM MgCl2, 0.02% Tween, 20% Human Serum. Let us know if you have any questions about its development or potential uses.

***This aptamer does not bind non phosphorylated ERK1 (aa 190-208) CIADPEHDHTGFLTEYVATR***

Target:   ERK1 (aa190-208) Phospho aa202

Target Species:   multi-species

Target Type:   peptide

Dissociation Constant (Kd):   12.9 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.


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Protocols

 

 

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Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200