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Aptamers

Aptamers: Catalogue Aptamers

Important information

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ERK1 (aa190-208)

ATW0091 Aptamer to ERK1 (aa 190-208) Protein Peptide

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
ATW0091-100ERK1 (aa190-208)10 AEU (100ug) POA Quantity Add to Order
ATW0091-25ERK1 (aa190-208)2.5 AEU (25ug) POA Quantity Add to Order

Description

ERK1 (Mitogen-activated protein kinase 3, also known as ERK1) is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and ERK1 (aa 190-208) peptide CIADPEHDHTGFLTEYVATR as a target.

***This aptamer does not bind phosphorylated aa202 pERK1 (aa 190-208) CIADPEHDHTGFL(t)EYVATR***

DataSheet

Target:   ERK1 (aa190-208)

Target Species:   human

Target Type:   peptide

Dissociation Constant (Kd):   10.1 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.


If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

DataSheet

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200