Cambio - Excellence in Molecular Biology


Aptamers: Modifications

Aptamers are single-stranded DNA or RNA molecules that can bind to pre-selected targets including proteins and peptides with high affinity and specificity. We offer catalogue aptamers (below); see the description tab (below) for details of our custom aptamer service.

When contacting us for pricing details of custom or catalogue aptamers it would assist our team to know the following information in order to provide accurate pricing. 

1- What modifications you require (see list below)?

2- Which end of the aptamer you require the modification(s): 3' , 5', or both?

3- How much aptamer you require (25 ug, 50 ug or 100 ug etc)?

4- What purification methods you require (we offer HPLC and PAGE)?

5- What the intended downstream application will be for the aptamer (?) - This allows our manufacturing team to prepare your aptamers using the most suitable methods.

6- Any other information that you feel may be relevant.

List of Modifications available (others are available)

ATWUNMOD - Unmodified

ATWAMINE - Amine modification

ATWBIOTIN - Biotin modification

ATWTHIOL - Thiol modification (extra charge)

Please note: Thiol reducing buffer is not supplied and users must provide their own

ATWFLUOR - Fluor (all) modification (extra charge)

If you are not sure or need any assistance then please feel free to pick up the phone and call us or contact us on Our team will be happy to guide you through the process.