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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

MMP-3

Matrix Metalloproteinase 3 (MMP-3) Aptamer ATW0062

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
  • Change to:
  • £
ATW0062-100MMP-310 AEU (100ug) POA Quantity Add to Order
ATW0062-25MMP-32.5 AEU (25ug) POA Quantity Add to Order

Description

Matrix metalloproteinase-3, also called Stromelysin-1, is an enzyme that degrades fibronectin, laminin, gelatins, collagens, and cartilage proteoglycans. Elevation of MMP-3 has been linked to metastatic osteosarcoma.

Target:   MMP-3 (Matrix Metalloproteinase-3)

Target Species:   murine

Target Type:   protein

Affinity Constant (Kd):   12.5 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

DataSheet

0.1uM synthesis scale (20-200ug)
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)


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Protocols

DataSheet

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References

Huang, J.F. et al. (2016) Elevated expressiopn of matrix metalloproteinase-3 in human osteosarcoma and its association with tumor metastasis. J. BUON. 21(1):235-43.

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Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Related products

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