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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

CD19 Aptamer to Human Protein Target

CD19 (hu) ATW0013

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
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  • £
ATW0013-100CD19 (hu) 10 AEU (100ug) POA Quantity Add to Order
ATW0013-25CD19 (hu) 2.5 AEU (25ug) POA Quantity Add to Order

Description

ATW0013 Aptamer to Human Protein Target, CD19

Datasheet

B lymphocyte antigen CD19 also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is found on the surface of B cells, a type of white blood cell.  It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Recombinant CD19 Human Proteins, [Sino Biological Inc., Cat# 11880-H08H] as a target and 1X PBS, pH = 7.4.  Let us know if you have any questions about its development or potential uses.

Target:   CD19

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   6.9 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

 

Custom aptamers can be developed; please contact us for details.

 

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

Datasheet

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Notes

Antibody Equivalent Units (AEU).  There is a  large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da).   We provide our aptamers in terms of moles, where the aptamer moles in 1  AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200