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Oligo Synthesis

Oligo Synthesis : CEPs

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Dithiol Serinol Phosphoramidite

3-Dimethoxytrityloxy-2-(3-((R)-a-lipoamido)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Glen Research

Catalogue No.DescriptionPack SizePriceQty
10-1991-02Dithiol Serinol Phosphoramidite0.25g £532.00 Quantity Add to Order
10-1991-90Dithiol Serinol Phosphoramidite100µmoles £195.00 Quantity Add to Order
10-1991-95Dithiol Serinol Phosphoramidite50umoles £109.00 Quantity Add to Order

Description

3-Dimethoxytrityloxy-2-(3-((R)-α-lipoamido)propanamido)propyl-1-O- (2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite
Formula: C44H61N4O7PS2 M.W.: 853.08 F.W.: 412.46
Diluent: Anhydrous Acetonitrile
Coupling: No changes needed from standard method recommended by synthesizer manufacturer.
Deprotection: Deprotect as required by nucleobases.
Storage: Freezer storage, -10 to -30°C, dry
Stability in Solution: 2-3 days
Please Note: This product is covered by US Patent No.: 8,394,948.

Modifiers
Labelling

Dithiol serinol CEP

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Protocols

Safety Data Sheet

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References

Glen Report 27.1: New Products - Dithiol Serinol Phosphoramidite and 3'- Dithiol Serinol CPG

 

 

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Notes

DILUTION/COUPLING DATA

The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures. Please link for more detailed usage information with the various synthesizers.

ABI 392/394
Cat.No. Pack Size Grams/ Pack 0.1M Dil. (mL) LV40 LV200 40nm 0.2µm 1µm 10µm
Approximate Number of Additions
10-1991-02 0.25grams .25grams 2.93 84.33 50.6 31.63 23 16.87 4.22
10-1991-90 100µmoles .085grams 1 20 12 7.5 5.45 4 1
10-1991-95 50µmoles .043grams .5 3.33 2 1.25 .91 .67 .17
Expedite
Cat.No. Pack Size Grams/ Pack Dilution (mL) Molarity 50nm 0.2µm 1µm 15µm  
Approximate Number of Additions
10-1991-02 0.25grams .25grams 4.37 .07 81 50.63 36.82 5.06  
10-1991-90 100µmoles .085grams 1.5 .07 23.6 14.75 10.73 1.48  
10-1991-95 50µmoles .043grams .75 .07 8.6 5.38 3.91 .54  
Mermade
Cat.No. Pack Size Grams/ Pack Dilution (mL) Molarity 30nm 200nm 1000nm    
Approximate Number of Additions
10-1991-02 0.25grams .25grams 4.37 .07 82.6 51.63 37.55    
10-1991-90 100µmoles .085grams 1.5 .07 25.2 15.75 11.45    
10-1991-95 50µmoles .043grams .75 .07 10.2 6.38 4.64

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Related products

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