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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

IFN gamma (bovine) Aptamer

Aptamer to Bovine Interferon Gamma (IFN?) Cytokine

Base Pair Bio

Description

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons and is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNγ is an important activator of macrophages. Aberrant IFNγ expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFNγ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects.

Target:   IFN Gamma

Target Species:   bovine

Target Type:   protein

Affinity Constant (Kd):   33.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Aptamer information Kd 33.7 ± 6.0 nM

IFNγ ATW0036 #1243 datasheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

IFNγ ATW0036 #1243 datasheet

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200