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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Peroxiredoxin-4 Aptamer

Peroxiredoxin-4 Aptamer

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
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  • £
ATW0029-100Peroxiredoxin 10 AEU (100ug) POA Quantity Add to Order
ATW0029-25Peroxiredoxin 2.5 AEU (25ug) POA Quantity Add to Order

Description

Peroxiredoxin-4 is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and recombinant? Peroxiredoxin-4 Protein, [Novus Biologicals (Cat# NBP1-41141]? as a target.

Target:   Peroxiredoxin-4

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   22.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

DataSheet

0.1uM synthesis scale (20-200ug)
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)



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Protocols

DataSheet

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Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Related products

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