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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Human IgG Fc Aptamer to Human Protein Target

IgG Fc (hu plasma)

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
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ATW0018-25IgG Fc (hu plasma)2.5 AEU (25ug) POA Quantity Add to Order
ATW0018-50IgG Fc (hu plasma)5.0 AEU (50ug) POA Quantity Add to Order

Description

Human Immunoglobulin G (IgG) is an antibody isotype. It is a protein complex composed of four peptide chains; two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers. The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. Representing approximately 75% of serum immunoglobulins in humans, IgG is the most abundant antibody isotype found in the circulation

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Immunoglobulin G plasma protein, [Athens Research Cat #16-16-090707-FC] as a target and 1X PBS pH 7.4.  Let us know if you have any questions about its development or potential uses.

Aptamer information Kd 8.6 ± 2.0 nM

Datasheet

Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Protocols

Datasheet

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Notes

Antibody Equivalent Units (AEU). There is a  large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da). We provide our aptamers in terms of moles, where the aptamer moles in 1  AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200