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Aptamers

Aptamers: Catalogue Aptamers

Important information

Do you know what modifications you will need for your aptamers?  see "modifications" section for details

Human Serum Albumin (HSA) ATW0086

Alpha Human Serum Albumin (HSA) Aptamer to Human Protein Target

Base Pair Bio

Catalogue No.DescriptionPack SizePriceQty
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ATW0086-100Human Serum Albumin (HSA)10 AEU (100ug) POA Quantity Add to Order
ATW0086-25Human Serum Albumin (HSA)2.5AEU (25ug) POA Quantity Add to Order

Description

Human serum albumin is the most abundant protein in human blood plasma. It is produced in the liver. Albumin constitutes about half of the blood serum protein. It is soluble and monomeric.  Albumin transports hormones, fatty acids, and other compounds, buffers pH, and maintains osmotic pressure, among other functions.

Target:   HSA (Human Serum Albumin)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   190.6 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods, library, and HSA protein, [Sigma Cat# A9511] as a target and 1X PBS, 1 mM MgCl2, and 0.05% Tween-20 in nuclease free water, pH 7.4.  Let us know if you have any questions about its development or potential uses.

Human Serum Albumin (HSA)

Image: COURTESY Borislav Mitev

Aptamer information Kd 190.6 ± 52.8 nM

ATW0086 #alphaFCHT3 datasheet 3.25.15

Other modifications available but not listed, pricing may be adjusted, Note in cart and Base Pair will contact you

Antibody Equivalent Units (AEU).  There is a  large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da).   We provide our aptamers in terms of moles, where the aptamer moles in 1  AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively

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Protocols

ATW0086 #alphaFCHT3 datasheet 3.25.15

 

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Notes

Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200

Related products

If you cannot find the answer to your problem then please contact us or telephone +44 (0)1954 210 200