Cambio - Excellence in Molecular Biology

In Vitro Toxicology

In Vitro Toxicology: Mutagenicity kits

The Ames II / Ames MPF Microfluctuation Assays are all modifications of the traditional Ames plate incorporation assay.

The Ames II assay uses the S. typhimurium strains TA98 and TAMix (a mixture of 6 strains, each detecting a specific base-pair substitution), whereas the Ames MPF® kits are available with the strains TA98, TA100, TA1535, TA1537, E.coli WP2 uvrA or E.coli WP2 pKM101.

 

Benefits of Xenometrix Ames Mutagenicity Assays over traditional Ames Procedures

  • Easy, compact and high throughput liquid format with 384 well plates.

  • Simple detection method with easy "readout" (as compared to the traditional assay)

  • Kits include all five types strains cited in OECD 471 (CoA supplied), quality controlled according to the same guideline 

  • Much less  test compound required.  (10 mg per strain if tested in triplicates, +/- S9, 6 semi-logarithmic compound dilutions)

  • Ames MPF is the preferred system for genotoxic impurities due to its low consumption of compound

  • Significantly less consumption of S9

  • Less environmental pollution due to significantly less "contaminated" waste

  • Less user intervention

  • Download presentation 

Ames MPF - Ready to use Media

for use with Ames kits, growth

Xenometrix AG

Catalogue No.DescriptionPack SizePriceQty
XPMM-EM02Ames MPF Salmonella Exposure Medium (RT)50ml £48.00 Quantity Add to Order
XPMM-GM00Ames Growth Medium (RT)50ml £48.00 Quantity Add to Order
XPMM-IM10Ames MPF Salmonella Reversion Indicator Medium (RT) - 550 ml550ml £147.00 Quantity Add to Order

Description

Ames MPF - Ready to use Media for Ames MPF kits

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