Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans).
This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Fibronectin from bovine plasma, [Sigma Cat #F4759] but was also affinity tested with human plasma fibronectin, Advanced BioMatrix, San Diego, CA [Part No. 5050] as a target. Both selection and validations done in 20 mM Tris, 100 mM NaCl, 0.005% Tween20 in nuclease free water, pH 7.4. Let us know if you have any questions about its development or potential uses.
Target: Fibronectin
Target Species: bovine, human
Target Type: protein
Affinity Constant (Kd): 1.7 nM
Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.
Aptamer information Kd 1.74nM
Datasheet
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)
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